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UK team gets $1.5 million NIH grant to continue success with cell-level study of Alzheimer's disease factor
University of Kentucky researchers have provided the first direct evidence that activated astrocytes could play a harmful role in Alzheimer's disease.
A UK news release explains, "The astrocyte is a very abundant non-neuronal cell type that performs absolutely critical functions for maintaining healthy nervous tissue. However, in neurodegenerative diseases, like Alzheimer?s disease, many astrocytes exhibit clear physical changes often referred to as 'astrocyte activation.' The appearance of activated astrocytes at very early stages of Alzheimer's has led to the idea that astrocytes contribute to the emergence and/or maintenance of other pathological markers of the disease."
UK researchers gave mice gene therapy at a very young age and assessed them 10 months later. The astrocyte activation improved brain function and preserved cognitive function. The research, published recently in the Journal of Neuroscience, has led to a five-year, $1.5 million National Institutes of Health funding grant to the researchers and the UK Sanders-Brown Center on Aging to further this line of study. Chris Norris, an associate professor in the UK College of Medicine Department of Molecular and Biomedical Pharmacology, is the senior author of the study. (Read more)
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Study Finds That Early Memory Loss Can Be A Predictor Of Dementia
Experiencing memory loss early in life could be a cause for concern about dementia later in life. Research from the University of Kentucky's Sanders-Brown Center on Aging has found that "self-reported memory loss is a strong predictor of clinical...
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New Research Argues That Alzheimer's Disease Should Rank As Third Most Common Cause Of Death In The U.s.
Alzheimer's disease may contribute to almost as many deaths in the U.S. as heart disease or cancer, says a recent study published in Neurology. Alzheimer's is listed as the nation's sixth leading cause of death, far behind the leading...
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Study Says Loss Of Smell May Help Sniff Out Alzheimer's Disease
A small pilot study of patients displaying signs of cognitive decline found that peanut butter can help identify those with Alzheimer?s disease, which is often accompanied by a loss of smell. The results indicate that loss in sense of smell may help in...
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National Effort To Combat Alzheimer's Disease Begins; As Research Continues, There Are Preventive Steps You Can Take
Country singer Glen Campbell, who has Alzheimer's disease, stands with wife Kim during a national conference Tuesday. Associated Press photo by Charles Dharapak.With numbers expected to jump to 16 million Americans by 2050, research is being conducted...
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Free Conference On Alzheimer's In Louisville Sept. 17
A Washington-based geriatric researcher will join University of Louisville researchers and clinicians a free conference examining Alzheimer?s disease from 9 a.m. to 3 p.m., Saturday, Sept. 17, at the Crowne Plaza Louisville Airport Hotel, 830 Phillips...
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